Welcome to the Rutter Lab

Welcome to the
Rutter Lab

The mission of our laboratory is to use functional genomics at the cellular and whole organism level to find new ways to enhance insulin secretion in diabetes mellitus.

Calcium imaging in an islet
Imaging islet connectivity
Insulin exocytosis from a single beta cell (Tsuboi et al)
mitochondria in 3D
Beta cell mitochondria

About Rutter Lab

Mission & Value

Rutter Lab is a cutting-edge research laboratory focused on diabetes mellitus, specifically studying insulin secretion and its fundamental signaling pathways by leveraging genome-wide studies, advanced imaging techniques, and molecular biology.

Innovation

Advancing research through state-of-the-art technology.

Precision

Using data-driven methods for accuracy.

Collaboration

Partnering with researchers and institutions globally.

Impact

Aiming to create meaningful change in diabetes treatment.

Recent Publications

Original PaperS

  1. Salazar, S., Delgadillo-Silva, L.F., Carapeto, P., Dakessian, K., Melhem, R., Provencher-Girard, A., Ostinelli, G., Turgeon, J., Kaci, I., Migneault, F, Huising, M.O., Hebert, M-J., and Rutter, G.A. Sex-dependent additive effects of dorzagliatin and incretin on insulin secretion in a novel mouse model of GCK-MODY. Diabetes in press (2026)
  2. Delgadillo-Silva, L., Dakessian, K., Provencher-Girard, A., Louch, W.E., Rutter, G.A. ER Calcium stores contribute to glucose-induced Ca2+ waves and intercellular connectivity in mouse pancreatic islets. Cell Calcium in press (2026)

ReviewS

  1. Behrens, P., Champagne, C.M., Halford, J.C.G., Moodie, M., Mooney, V., Proietto, J., Rutter, G.A., Samara, K. and Holly, J.M.P. The obesity challenge: sicen and solutions – overlaps with the climate crisis, Frontiers in Science, in press (2025).
  2. Tang, A., Lepage, M., Rutter, G.A., Carpentier, A.C. Editorial: In vivo magnetic resonance imaging of metabolic disorders. Endocr 16:1713999 (2025)

Guy Rutter awards and recognitions

2025

Elected as a new Fellow to the Academy of Medical Sciences

2023

Sir Philip Randle Lectureship, Biochemical Society

2020

Albert Renold Award, EASD

2014

Dorothy Hodgkin Lectureship of Diabetes UK

Contact Us to get more info

Need more information or have specific inquiries? Our dedicated support team is here to assist you.

Lab Manager:

Audrey Provencher-Girard:

Send us a message