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Cherkaoui, I., Du, Q., Egli, D., Misra, M and Rutter, G.A. Optimized Protocol for Generating Functional Pancreatic Insulin-secreting Cells from Human Pluripotent Stem Cells. Journal of Visualised Experiments (JoVe) https://www.jove.com/t/65530/optimized-protocol-for-generating-functional-pancreatic-insulin
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Slieker, R.C., Munch, M., Donnelly, L.A., Bouland, G., Dragon, I., Kuznetsov, D, Elders, P., Rutter, G.A., Ibberson, M., Pearson, E.R., ‘t Hart, L.M., van de Wiel, M.A., and Beulens, J.W.L. A multi-omics machine learning approach to predict diabetes progression: a RHAPSODY study. In press at Diabetologia (2024)
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Yu, V., Yong, F., Marta, A., Khadayate, S., Osakwee, A., Bhattacharya, S.S., Varghese, S.S., Chabosseau, P., Tabibi, S.M., Chen, K., Georgiadou, E., Parveen, N., Suleiman, M., Stamoulis, Z., Marselli, L., de Luca C., Tesi, M., Ostinelli, G., Delgadillo Silva, L., Wu, X., Hatanaka, Y., Montoya, A., Elliot, J., Patel, B., Demchenko, N., Wilding C., Hajkova, […]
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Li, S., Dragan,, I, Tran, V.D.T., Fung, C.H., Kuznetsov, D., Hansen, M.K., Beulens, J.W.J., ’t Hart, L.M., Slieker, R.C., Donnelly, L.A., Gerl, M.J., Klose, C., Mehl, F., Simons, K., Elders, P.J.M., Pearson, E.P., Rutter, G.A*. and Ibberson, M.* Multi-omics clusters associated with progression in type 2 diabetes: an IMI-RHAPSODY Study. Front. Endo, 15:1350796. doi: 10.3389/fendo.2024.1350796. 22 […]
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Ghiasi, S.M., Marchetti, P., Piemonti, L., Nielson, J.N., Porse, B.Y., mandrup-Poulse, T., and Rutter, G.A. Proinflammatory Cytokines, but not Glucolipotoxicity, Suppress Nonsense-Mediated RNA Decay to Impair Regulated Transcript Isoform Processing in Pancreatic β-Cells. Front. Endo., Mar 22;15:1359147. doi: 10.3389/fendo.2024.1359147 (2024)
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Hu, M., Kim, I., Moran, I., Peng, W., Sun, O., Bonnefond, A., Bonas-Guarch, S., Froguel, P., Rutter, G.A. Multiple Genetic variants at the SLC30A8 locus affect local super-enhancer activity and influence pancreatic β cell survival and function FASEB J 38(8):e23610. doi: 10.1096/fj.202301700RR (2024).
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Cuozzo, F., Viloria, K., Shileh, A.H., Nasteka, D., Frazer-Morris, C., Tong, J., Jiao, Z., Boufersaoui, A., Marzullo, B., Rosoff, D.B., Smith, H.R., Bonner, C., Kerr-Conte, J., Pattou, F., Nano, R., Piemonti, L., Johnson, P.R.V., Speirs, R., Roberts, J., Lavery, G.G., Clark, A., Ceresa, C.D.L., Ray, D.W., Hodson, L., Davies, A., Rutter, G.A., Shima, M., Scharfmann, […]
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Suba, K., Patel, Y., Roberts, A. Martin Alonso, A., Roberts, A., Hansen, B., Norton, M., Shrewsbury, J.V., Chen, S, Kwok, R., Kalogianni, V., Chen, S., Liu, X., Rutter, G.A., Jones, B., Minnion, J., Owen, B., Distaso, W., Drucker, D.J., Tan, M., Bloom, S.J., Murphy, K., Salem, V. Intra-islet glucagon regulates pulsatile insulin secretion and glucose […]
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Delgadillo Silva, L.F., Singh, S.P., Georgiadou, E., Rutter, G.A.* and Ninov, N. Optical interrogation of β-cell activity in situ identifies two highly functional subpopulations of pancreatic β-cells” in press Sci Adv (2024) *Co-corresponding author
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Manchanda, Y., ElEid, L., Oqua, A.I., Ramchunder, Z., Choi, J., Shchepinova, M.M., Rutter, G.A., Asuka Inoue, A., Tate, E.W., Jones, B., and Tomas, A. Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling. In press Science Signalling, 2024