Happy Hours for Lab Rutter in a Microbrewery in Montreal’s “Quartier Latin”
Guy Rutter participated to HIRN 2025, Washington DC, USA
A new article was published
Dolgin V, Chabosseau P, Bistritzer J, Noyman I, Staretz-Chacham O, Wormser O, Hadar N, Eskin-Schwartz M, Kanengisser-Pines B, Narkis G, Abramsky R, Shany E, Rutter GA, Marks K, Birk OS. Severe neonatal hypotonia due to SLC30A5 variant affecting function of ZnT5 zinc transporter. JIMD Rep. 2025 Jan 9
PMID: 39790720
Ayush Mehra joined the team as a Ph.D. student. Welcome in !
A new article was published
Cherkaoui I, Du Q, Egli DM, Dion C, Leitch HG, Sachedina D, Misra S, Rutter GA. Investigating the pathogenicity of the recessive HNF1A p.A251T variant in monogenic diabetes using iPSC-derived beta-like cells. medRxiv [Preprint]. 2024 Dec 11
PMID: 39711726
A new article was published
Lopez-Noriega L, Callingham R, Martinez-Sánchez A, Nawaz S, Pizza G, Haberman N, Cvetesic N, Nguyen-Tu MS, Lenhard B, Marchetti P, Piemonti L, de Koning E, Shapiro AMJ, Johnson PR, Leclerc I, Hastoy B, Gauthier BR, Pullen TJ, Rutter GA. Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell function. iScience. 2024 Dec 9
PMID: 39811653
Funding Announcement Breakthrough T1D Grant
Project Title: A combined chemical synthetic / intravital imaging approach to explore the survival and function of human pluripotent derived islets after transplantation in mice.
Funding to be activated 2025 01 05.
Rutter Lab participated to Diabetes Canada and CIRTN-R2FIC meetings 2024, in Halifax, Canada. Guy, Luis, Shadai, Priscila and Ya-Chi participated.
A new article was published
Li S, Arora S, Attaoua R, et al. Leveraging hierarchical structures for genetic block interaction studies using the hierarchical transformer. Preprint. medRxiv. 2024;2024.11.18.24
317486. Published 2024 Nov 18.
PMID: 39606365
A new article was published
Salazar S, Delgadillo-Silva LF, Carapeto P, Dakessian K, Melhem R, Provencher-Girard A, Ostinelli G, Turgeon J, Kaci I, Migneault F, Huising MO, Hébert MJ, Rutter GA. Sex-dependent additive effects of dorzagliatin and incretin on insulin secretion in a novel mouse model of GCK-MODY. bioRxiv [Preprint]. 2024 Nov 11
PMID: 39605321
A new article was published
El Eid L, Deane-Alder K, Rujan RM, Mariam Z, Oqua AI, Manchanda Y, Belousoff MJ, Bernardino de la Serna J, Sloop KW, Rutter GA, Montoya A, Withers DJ, Millership SJ, Bouzakri K, Jones B, Reynolds CA, Sexton PM, Wootten D, Deganutti G, Tomas A. In vivo functional profiling and structural characterisation of the human Glp1r A316T variant. bioRxiv [Preprint]. 2024 Nov 10
PMID: 39484598
An erratum was published
Rutter GA, Gresch A, Delgadillo Silva L, Benninger RKP. Exploring pancreatic beta-cell subgroups and their connectivity. Nat Metab. 2024 Nov;6(11):2039-2053.
PMID: 39117960
Rutter Lab has a meeting in University of Toronto with “Breakthrough Type 1 Diabetes” collaborators around the T1D project. Guy, Shadai, Priscila and Giada participated.
Happy Hours for Lab Rutter in an Irish Pub on Crescent Street
Rutter Lab participed to EASD 2024 Meeting in Madrid, Spain. Guy, Marie and Inès participated.
Guy Rutter is elected as a Fellows at the Academy of Medical Science. Link to the Press Release. A celebration in the Cardiometabolic Axis in CRCHUM took place in the afternoon.
Conference: Participation to Boston Ithaca Islet Club (BIIC) 2025, taking place in CRCHUM this year.
The whole group invited to a ski trip to Mont Orford.
Happy Hours for Lab Rutter in a Microbrewery in Montreal’s “Quartier Latin”
Guy Rutter participated to HIRN 2025, Washington DC, USA
A new article was published
Dolgin V, Chabosseau P, Bistritzer J, Noyman I, Staretz-Chacham O, Wormser O, Hadar N, Eskin-Schwartz M, Kanengisser-Pines B, Narkis G, Abramsky R, Shany E, Rutter GA, Marks K, Birk OS. Severe neonatal hypotonia due to SLC30A5 variant affecting function of ZnT5 zinc transporter. JIMD Rep. 2025 Jan 9
PMID: 39790720
Ayush Mehra joined the team as a Ph.D. student. Welcome in !
A new article was published
Cherkaoui I, Du Q, Egli DM, Dion C, Leitch HG, Sachedina D, Misra S, Rutter GA. Investigating the pathogenicity of the recessive HNF1A p.A251T variant in monogenic diabetes using iPSC-derived beta-like cells. medRxiv [Preprint]. 2024 Dec 11
PMID: 39711726
A new article was published
Lopez-Noriega L, Callingham R, Martinez-Sánchez A, Nawaz S, Pizza G, Haberman N, Cvetesic N, Nguyen-Tu MS, Lenhard B, Marchetti P, Piemonti L, de Koning E, Shapiro AMJ, Johnson PR, Leclerc I, Hastoy B, Gauthier BR, Pullen TJ, Rutter GA. Roles for the long non-coding RNA Pax6os1/PAX6-AS1 in pancreatic beta cell function. iScience. 2024 Dec 9
PMID: 39811653
Funding Announcement Breakthrough T1D Grant
Project Title: A combined chemical synthetic / intravital imaging approach to explore the survival and function of human pluripotent derived islets after transplantation in mice.
Funding to be activated 2025 01 05.
Rutter Lab participated to Diabetes Canada and CIRTN-R2FIC meetings 2024, in Halifax, Canada. Guy, Luis, Shadai, Priscila and Ya-Chi participated.
A new article was published
Li S, Arora S, Attaoua R, et al. Leveraging hierarchical structures for genetic block interaction studies using the hierarchical transformer. Preprint. medRxiv. 2024;2024.11.18.24
317486. Published 2024 Nov 18.
PMID: 39606365
A new article was published
Salazar S, Delgadillo-Silva LF, Carapeto P, Dakessian K, Melhem R, Provencher-Girard A, Ostinelli G, Turgeon J, Kaci I, Migneault F, Huising MO, Hébert MJ, Rutter GA. Sex-dependent additive effects of dorzagliatin and incretin on insulin secretion in a novel mouse model of GCK-MODY. bioRxiv [Preprint]. 2024 Nov 11
PMID: 39605321
A new article was published
El Eid L, Deane-Alder K, Rujan RM, Mariam Z, Oqua AI, Manchanda Y, Belousoff MJ, Bernardino de la Serna J, Sloop KW, Rutter GA, Montoya A, Withers DJ, Millership SJ, Bouzakri K, Jones B, Reynolds CA, Sexton PM, Wootten D, Deganutti G, Tomas A. In vivo functional profiling and structural characterisation of the human Glp1r A316T variant. bioRxiv [Preprint]. 2024 Nov 10
PMID: 39484598
An erratum was published
Rutter GA, Gresch A, Delgadillo Silva L, Benninger RKP. Exploring pancreatic beta-cell subgroups and their connectivity. Nat Metab. 2024 Nov;6(11):2039-2053.
PMID: 39117960
Rutter Lab has a meeting in University of Toronto with “Breakthrough Type 1 Diabetes” collaborators around the T1D project. Guy, Shadai, Priscila and Giada participated.
Happy Hours for Lab Rutter in an Irish Pub on Crescent Street
Rutter Lab participed to EASD 2024 Meeting in Madrid, Spain. Guy, Marie and Inès participated.
The mission of our laboratory is to use functional genomics at the cellular and whole organism level to find new ways to enhance insulin secretion in diabetes mellitus.
